Karolinska Institutet (KI), founded in 1810, is Sweden’s only university especially focusing on biomedical sciences. In addition, KI annually awards the Nobel Prize in Physiology or Medicine. KI ranks as one of the world’s leading medical universities, thanks in part to the quality of its research activities, which today account for 40 per cent of all medical research in Sweden. KI has about 4 800 employees (full-time equivalents), nearly two-thirds of whom are female. Some 80 per cent of KI’s income is devoted to research, distributed among some 600 research groups covering all medical fields. KI provides excellent postgraduate training with 2200 registered PhD students from around the world who are active in both basic and clinical research. Research at KI has a strong European dimension, with almost 200 project participations within the EU’s now closed Sixth Framework Programme (FP6). Of these, KI coordinated 28 projects. KI is a major player in FP7, participating in some 323 projects including 36 as coordinator as well as 31 European Research Council Grants. KI has to date been awarded 123 contracts within Horizon 2020. KI is also a major European beneficiary of funds from the National Institutes of Health in the U.S. The Academic Primary Care centre (APC) is an umbrella organisation, coordinating primary care science and process development within Stockholm County Council (SCC) and all Primary Health Care centres (PHCs) >200. It bridges the gap between Karolinska Institute with basic research and the clinical county council. It further consists of eight Academic nodes (AVC), each coordinated by eight associated researchers that are responsible for research activities, education and development in >50 primary care units (primary health care centres, rehabilitation centres, dietitians, motherhood and child care etc.). The main academic affiliation of APC is through the Department of Neurobiology, Care Sciences and Society Division of Family Medicine and Primary Care, at Karolinska Institutet, Stockholm, Sweden.